Potential medicinal effects and applications of stevia constituents

The application of stevia glycosides in the food industry has grown steadily last two decades. Besides use its constituents as natural sweeteners, increasing attention been given to their potential health benefits and therapeutic applications. Whereas some cases clinical studies have realized (prominently, investigate hypoglycemic antihypertensive activity) many them failed cover expectations from preclinical investigations. Here, we review current knowledge on constituents’ pharmacokinetics (both rodents humans) most profusely investigated medical/health-related applications: i.e. diabetes metabolic syndrome, hypertension, antimicrobial anticancer activity. outcome available perspectives Stevia uses are discussed connection with knowledge.